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The subject of intentional breeding or meat rabbits is prohibited. The answers provided on this board are for general guideline purposes only. The information is not intended to diagnose or treat your pet. It is your responsibility to assess the information being given and seek professional advice/second opinion from your veterinarian and/or qualified behaviorist.
The live yeast Saccharomyces cerevisiae(CNCM I-4407) 4b1702 to help repopulate the intestine with beneficial micro-organisms. To my knowledge there are currently two types of probiotics that have been shown useful for rabbits. The best tested one is live brewer’s yeast (saccaromyces cerevisiae), the other one is enterococcus faecium. e. faecium is the most prevalent gut bacteria of healthy rabbits. Lactobacillus like acidophilus and other lactic acid microbes that we find in yoghurt and other fermented dairy-products are less effective, they seem not to be able to survive the very strong stomach acid of the rabbit.In this study, dairy with B. subtilis significantly improved concentrations of the serum immunoglobulins IgG and IgA of rabbits. Moreover, the relative weights of the spleen were significantly increased by dietary supplementation with B. subtilis after 5 weeks of feeding. It can thus be deduced that B. subtilis might improve immune function, which has been reported to reduce weaning stress and improve the growth performance of rabbits at weaning ( 30). It has been reported that Bacillus cereus increased the concentrations of beneficial bacteria and decreased the concentration of harmful bacteria ( 31). In the current study, the relative abundance of Bacteroides and Clostridium were significantly decreased, and Ruminococcus increased after feeding B. subtilis. The Ruminococcus contributed to the digestion and absorption of fiber in herbivores ( 32). The increase of Ruminococcus may promote the growth performance of rabbits. In addition, the increase of Bacteroides and Clostridium in the intestine leads to colitis and carcinogenesis ( 33). These findings indicate that dairy with B. subtilis can regulate intestinal flora and maintain intestinal health. Probiotics are also not a one and done fix. To sustain benefits once the appropriate probiotic is identified, the animal must consume the probiotic regularly.
Benebac is a type of probiotics that several members here are using with their bunnies. It’s a powder that you sprinkle over food (wet greens). It’d not be bad to give to both your rabbits. The British rabbit vet Molly Varga, author of the 2nd edition of the Textbook Of Rabbit Medicine says yes to giving probiotics to rabbits, they can’t harm.Pro-Fibre for Rabbits A palatable high-fibre pellet to encourage normal digestive function in rabbits Description Not all the studies about the dietary administration of probiotics in rabbits reported modification in the intestinal morphology. For instance, Pogány Simonová et al. [ 32] and Oso et al. [ 45] did not report modification in jejunal morphometry or morphological parameters in the rabbit ileum after probiotic inclusion ( E. faecium and a mix of Pediococcus acidilactici and Bacillus cereus, respectively). The following medications may reduce the efficacy of probiotics when given at the same time: antibiotics, antifungals.
Studies are limited for this supplement and therefore information regarding side effects is also limited. However, probiotics are considered very safe and have few reported side effects. Rarely, probiotics have been reported to cause gas, stomach upset, or stomach discomfort, particularly when first taking the supplement. To evaluate the effect of probiotic supplementation in diets on the immune response, some authors took into account specific and non-specific immune response. For this reason, different haematological parameters were analysed, mainly total protein, immunoglobulins, white blood count (WBC), and lymphocytes. The studies reported variations in the results, and the reasons for that could be related to the use of different types and doses of probiotics, as well as differences in feed composition and mechanism of action which characterised different probiotics. Only at the end of the century the role of gut flora and the protective function of bacteria against pathogens were cleared and some fermented foods were considered probiotic products due to the presence of one or more probiotic bacteria [ 12]. In return, the survival rate of rabbits fed B. subtilis was higher than that of the controls after they were challenged with E. coli. This conclusion was supported by increased body weights, serum immunoglobulin, and immune organ index and enhanced expression of major innate immunity genes involved in initiating and regulating immune response against E. coli. It is worth noting that β-defensin was significantly upregulated in the B. subtilis feeding group postinfection with E. coli, especially DEFB 114, DEFB 134, and DEFB 135. Given that β-defensin has a strong antibacterial ability, the higher expression of β-defensin may be the most important reason for disease resistance. Meanwhile, the present results showed that the number of E. coli in the cecal contents significantly declined with a diet of B. subtilis during the test days. As various reports have shown, several bacilli have established antimicrobial properties against various Gram-positive and Gram-negative pathogenic bacteria ( 46). In this study, BYS2, BQ3, and BD17 have also shown strong inhibition against E. coli in vitro and therefore possess potent immunostimulatory capacities. It is also important that the intestinal flora is mainly composed of anaerobic bacteria, and relatively few aerobic bacteria. B. subtilis can inhibit the growth of pathogenic E. coli by consuming oxygen in the intestine and regulating the balance of intestinal flora. Previous research showed that B. subtilis PY79 hr can inhibit colonization and persistence of Salmonella enteritidis, C. perfringens, and E. coli ( 47). In the intestine, B. subtilis may prevent the overgrowth of E. coli, enhance the resistance to E. coli invasion of the intestinal tract, and ameliorate disease processes. As a result, a diet including B. subtilis decreased the concentration of E. coli in vivo. B. subtilis may be competitive exclusion approaches in the control of infection with enteric pathogens. It is important to introduce dietary changes slowly to allow the gut to adjust. We recommend gradually building up to the required amount of over 7 days.
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As shown in Figure 7B, the number of E. coli in the heart and cecal contents in the B. subtilis group were declined compared to controls at 1 dpi. At 3 dpi, the number of E. coli in all tested tissues declined compared to those of 1 dpi. In particular, rabbits fed with the diet of B. subtilis had lower ( P< 0.05) E. coli content in their cecal contents compared to the controls at 3 dpi. Expression of Innate Immune-Related Genes in the Spleen and Jejunum of the Infected Rabbits Given daily, it can help promote efficient digestion and avoid the problems associated with insufficient dietary fibre. Imagine our delight recently when, perusing the array of rabbit food on the shelves of our local Tisol shop, I found a cylinder of American Pet Diet probiotic pellets. They go under the brand name “Critter Be Better” or CBB, and they’re a bit on the pricey side, but after all they are only supposed to be probiotic supplements for rabbits and not something you feel them a lot of every day. Some evidence suggests that probiotics can play several roles in rabbit farming, from biological control against pathogenic microorganisms, to growth enhancer or active compounds to increase the quantity and quality of the final product. The positive effects determined in rabbits fed the experimental diets are in general ascribed to the capacity of probiotics to interact with the host and with all the microbiota present in the different parts or organs of the GIT, modifying the entire production process. From the analysis of the different research studies emerges the findings that probiotics have different modes of action and that many factors can modify the responses, confirming that probiotic properties have bacterium–host specificity. Research of this type is especially important in terms of reducing the use of antibiotics for therapeutic purposes through nutritional prevention in animals. On the contrary, it must be taken also into consideration the possibility of an antagonistic effect of the microorganisms employed. About this eventuality, El-Badawi et al. [ 40] reported a negative association between Bacillus subtilis and Saccharomyces cerevisiae. The authors tested the bacteria alone (0.1% of bacterial dry media of 3 × 10 7 CFU/g, Enviva PRO, Dupont, USA) and the yeast (0.1% of dry live yeast of 10 8 CFU/g, RUMI YEAST Sc47, Neovia, France) along with their mix (0.05%, respectively) in comparison to a control diet in 8-week-old New Zealand White rabbits for 10 weeks. The results of the FCR highlighted that the rabbits fed the mix of microorganisms did not differ from the control, whereas the employment of the two probiotics alone increased it. Similarly, digestion coefficients of most measured nutrients (dry matter, organic matter, crude protein, and nitrogen-free extract) were higher in rabbits fed the two diets with the single cell type than their mix and the control (mix similar to control) [ 40].
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